Category Archives: Evolutionary genomics & Systems biology

Tuning protein interactions with post-translational modifications – 4 Novembre 2020

Posted on October 28, 2020 by Anna Fijarczyk

Journal club sur la génomique évolutive et la biologie des systèmes Winter DL, Iranmanesh H, Clark DS, and Glover DJ Design of Tunable Protein Interfaces Controlled by Post-Translational Modifications ASC Synthetic Biology doi: https://doi.org/10.1021/acssynbio.0c00208 Responsable de la discussion :  David … Continue reading →

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Mitonuclear incompatibilities in natural populations of leaf beetle – 21 Octobre 2020

Posted on October 15, 2020 by Anna Fijarczyk

Journal club sur la génomique évolutive et la biologie des systèmes Rank NE, Mardulyn P, Heidl SJ, Roberts KT, Zavala NA, Smiley JT, Dahlhoff EP Mitonuclear mismatch alters performance and reproductive success in naturally introgressed populations of a montane leaf … Continue reading →

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How mutations in the receptor binding domain of spike glycoprotein of SARS-CoV-2 affect affinity to ACE2 – 7 Octobre 2020

Posted on September 30, 2020 by Anna Fijarczyk

Journal club sur la génomique évolutive et la biologie des systèmes Starr TN, Greaney AJ, Hilton SK, Ellis D, Crawford KHD, …, Bloom JD Deep Mutational Scanning of SARS-CoV-2 Receptor Binding Domain Reveals Constraints on Folding and ACE2 Binding Cell … Continue reading →

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Adjacent codon pairs in yeast modulate translation efficiency – 23 septembre 2020

Posted on September 22, 2020 by Anna Fijarczyk

Journal club sur la génomique évolutive et la biologie des systèmes Gamble CE, Brule CE, Dean KM, Fields S, Grayhack EJ. 2016. Adjacent Codons Act in Concert to Modulate Translation Efficiency in Yeast Cell doi: https://doi.org/10.1016/j.cell.2016.05.070 Responsable de la discussion … Continue reading →

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Predicting protein interactions from coevolving residues – 6 Mars 2020

Posted on February 28, 2020 by Anna Fijarczyk

Journal club sur la génomique évolutive et la biologie des systèmes Cong Q, Anishchenko I, Ovchinnikov S, Baker D. 2019. Protein interaction networks revealed by proteome coevolution Science doi: 10.1126/science.aaw6718 Responsable de la discussion :  David Bradley du Landry Lab … Continue reading →

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Transcriptional scanning shapes germline mutation rates – 21 Février 2020

Posted on February 17, 2020 by Anna Fijarczyk

Journal club sur la génomique évolutive et la biologie des systèmes Xia B, Yan Y, Baron M, Wagner F, Barkley D, Chiodin M, Kim SY, Keefe DL, Alukal JP, Boeke JD, Yanai I. 2020. Widespread Transcriptional Scanning in the Testis … Continue reading →

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Scales of protein evolution constraint – 7 Fevrier 2020

Posted on January 31, 2020 by Anna Fijarczyk

Journal club sur la génomique évolutive et la biologie des systèmes Konaté MM, Plata G, Park J, Usmanova DR, Wang H, Vitkup D. 2019. Molecular function limits divergent protein evolution on planetary timescales eLife doi: https://doi.org/10.7554/eLife.39705.001 Responsable de la discussion … Continue reading →

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Tracking microbial populations at high resolution – 24 Janvier 2020

Posted on January 17, 2020 by Anna Fijarczyk

Journal club sur la génomique évolutive et la biologie des systèmes Nguyen Ba AN, Cvijović I, Rojas Echenique JI, Lawrence KR, Rego-Costa A, Liu X, Levy SF, Desai MM. 2019. High-resolution lineage tracking reveals travelling wave of adaptation in laboratory … Continue reading →

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Protein nanopore sequencing – 10 Janvier 2020

Posted on January 6, 2020 by Anna Fijarczyk

Journal club sur la génomique évolutive et la biologie des systèmes Ouldali H, Sarthak K, Ensslen T, Piguet F, Manivet P, Pelta J, Behrends JC, Aksimentiev A, Oukhaled A. 2019. Electrical recognition of the twenty proteinogenic amino acids using an … Continue reading →

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Interpreting transcription factors to predict expression level – 13 Décembre

Posted on December 6, 2019 by Anna Fijarczyk

Journal club sur la génomique évolutive et la biologie des systèmes Boer CG, Vaishnav ED, Sadeh R et al. 2019. Deciphering eukaryotic gene-regulatory logic with 100 million random promoters Nature Biotechnology doi:10.1038/s41587-019-0315-8 Responsable de la discussion :  Christian Landry Vendredi … Continue reading →

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