Category Archives: Evolutionary genomics & Systems biology

Experimental evolution of adaptive divergence in fission yeast – 7 avril 2021

Journal club sur la génomique évolutive et la biologie des systèmes Sergio Tusso, Bart P. S. Nieuwenhuis, Bernadette Weissensteiner, Simone Immler and Jochen B. W. Wolf 2021 Experimental evolution of adaptive divergence under varying degrees of gene flow Nature Ecology … Continue reading

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Generating antibiotic resistance determinants de novo – 24 mars 2021

Journal club sur la génomique évolutive et la biologie des systèmes Michael Knopp, Arianne M. Babina, Jónína S. Gudmundsdóttir, Martin V. Douglass, M. Stephen Trent, Dan I. Andersson 2021 A novel type of colistin resistance genes selected from random sequence … Continue reading

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Predicting expression divergence using 1000 yeast – 10 mars 2021

Journal club sur la génomique évolutive et la biologie des systèmes Dhaval Vaishnav, Carl G. de Boer, Moran Yassour, Jennifer Molinet, Lin Fan, Xian Adiconis, Dawn A. Thompson, Francisco A. Cubillos, Joshua Z. Levin, Aviv Regev 2021 A comprehensive fitness landscape … Continue reading

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Interfaces accumulate mutations which are deleterious in monomers – 24 février 2021

Journal club sur la génomique évolutive et la biologie des systèmes Hochberg GKA, Liu Y, Marklund EG, Metzger BPH, Laganowsky A & Thornton JW 2020 A hydrophobic ratchet entrenches molecular complexes nature doi: https://doi.org/10.1038/s41586-020-3021-2 Responsable de la discussion :  Angel … Continue reading

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The uses of structural protein readouts – 1 février 2021

Journal club sur la génomique évolutive et la biologie des systèmes Valentina Cappelletti, Thomas Hauser, Ilaria Piazza, … , Paola Picotti 2020 Dynamic 3D proteomes reveal protein functional alterations at high resolution in situ Cell doi: https://doi.org/10.1016/j.cell.2020.12.021 Responsable de la … Continue reading

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Can enhancers facilitate evolution of de novo genes? – 27 janvier 2021

Journal club sur la génomique évolutive et la biologie des systèmes Paco Majic and Joshua L Payne 2019 Enhancers Facilitate the Birth of De Novo Genes and Gene Integration into Regulatory Networks Molecular Biology and Evolution doi: https://doi.org/10.1093/molbev/msz300 Responsable de la … Continue reading

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Adaptive evolution of nontransitive fitness in yeast – 13 Janvier 2021

Journal club sur la génomique évolutive et la biologie des systèmes Sean W Buskirk, Alecia B Rokes, Gregory I Lang 2020 Adaptive evolution of nontransitive fitness in yeast eLife doi: 10.7554/eLife.62238 Responsable de la discussion :  Damien Biot-Pelletier du Landry … Continue reading

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Can directional selection drive evolvability? – 16 Decembre 2020

Journal club sur la génomique évolutive et la biologie des systèmes Zheng J, Guo N & Wagner A 2020 Selection enhances protein evolvability by increasing mutational robustness and foldability Science doi: 10.1126/science.abb5962 Responsable de la discussion :  Diana Ascencio du … Continue reading

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Introns: junk or not junk? – 2 Decembre 2020

Journal club sur la génomique évolutive et la biologie des systèmes Parenteau J, Elela SA 2019 Introns: Good Day Junk Is Bad Day Treasure Trends in Genetics doi: https://doi.org/10.1016/j.tig.2019.09.010 Responsable de la discussion :  Marika Drouin du Landry Lab Mercredi … Continue reading

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Gene loss can enhance yeast capacity to evolve and adapt – 18 Novembre 2020

Journal club sur la génomique évolutive et la biologie des systèmes Helsen J, Voordeckers K, Vanderwaeren L, Santermans T, Tsontaki M, Verstrepen KJ, Jelier R Gene Loss Predictably Drives Evolutionary Adaptation Molecular Biology and Evolution doi: https://doi.org/10.1093/molbev/msaa172 Responsable de la … Continue reading

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